Recurrence occurred postoperatively, and CA19 -9 increased to 1,850 U/mL. CT showed local recurrence in the pancreatic bed without distant metastasis. 18 months after the previous Whipple procedure. The diagnosis was local recurrence of pancreatic ductal adenocarcinoma after surgery.
Treatment Timeline
Phase
Details
Date
relapse assessment
proton therapy
concurrent chemotherapy
efficacy assessments
adjuvant therapy
Treatment Outcome
before
CA19 -9: 1,850 U/mL, local recurrence 18 months after Whipple surgery
after
CA19 -9 dropped to 95 U/mL (95% decrease), local CR, DFS 15 months, OS 24 months and ongoing
highlight
Japan's top proton center, proton therapy for local recurrence after surgery, CR efficacy