Idiopathic Pulmonary Fibrosis (IPF)
Patient Condition
The patient was presented with progressive dyspnea worsening for 3 years and had a history of smoking (20 pack-years). HRCT showed extensive honeycomb lung in both lungs. Lung function: FVC 38% predicted, DLCO 22% predicted. 6MWD 180m, mMRC score 4. Oxygen saturation resting at 88%. Advanced IPF was diagnosed (GAP score of 7, stage III). It was assessed to meet the indications for lung transplantation.
Treatment Timeline
| Phase | Details | Date |
|---|---|---|
| Pre-transplant evaluation | ||
| Waiting period treatment | ||
| double lung transplant | ||
| Post-operative rehabilitation (months 1-3) | ||
| Long-term follow-up (Months 4-12) |
Treatment Outcome
| before | FVC accounted for 38% of predicted value, DLCO accounted for 22% of predicted value, 6MWD 180m, mMRC score 4, resting SpO2 88%, GAP score 7 (Phase III) |
|---|---|
| after | 12 months after lung transplantation, FVC accounted for 85% of predicted value (47% improvement), DLCO accounted for 78% of predicted value (56% improvement), 6MWD 480m (300m improvement), mMRC score 1 |
| highlight | ECMO-assisted double lung transplantation was successful. Lung function returned to near normal levels 12 months after operation, and quality of life was completely improved, and normal life was returned. |