Idiopathic Pulmonary Fibrosis (IPF)
Patient Condition
The patient sought medical treatment due to dry cough and shortness of breath after exercise for 1 year. HRCT showed grid shadows and honeycomb changes in both lower lungs. Lung function: FVC 62% predicted, DLCO 48% predicted. 6MWD 370m, mMRC score 2. IPF was diagnosed (GAP score 3, stage I).
Treatment Timeline
| Phase | Details | Date |
|---|---|---|
| diagnostic assessment | ||
| treatment initiation | ||
| Standardized treatment (months 1-12) | ||
| Maintenance treatment (Months 13-24) |
Treatment Outcome
| before | FVC accounted for 62% of predicted value, DLCO accounted for 48% of predicted value, 6MWD 370m, mMRC score 2 |
|---|---|
| after | After 24 months of treatment, FVC accounted for 58% of the predicted value (annual decline rate of approximately 2%), DLCO accounted for 44% of the predicted value, 6MWD 375m, and mMRC score 2 |
| highlight | Pirfenidone treatment for 24 months effectively delayed the progression of IPF, with an annual decline in FVC of approximately 2%, which was well tolerated by patients |