Huntington's Disease (HD)
Patient Condition
Middle-advanced Huntington's disease, CAG repetition number 49, severe chore-like exercise, moderate cognitive decline, moderate depression, and significant weight loss. UHDRS TMS 50 points, TFC 6 points, and MoCA 14 points.
Treatment Timeline
| Phase | Details | Date |
|---|---|---|
| integrated assessment | ||
| Symptomatic medication treatment + nutritional support | ||
| Optimization of comprehensive symptomatic treatment | ||
| Long-term maintenance management |
Treatment Outcome
| before | UHDRS TMS 50, TFC 6, MoCA 14, severe choreo-like exercise, moderate cognitive decline, moderate depression, malnutrition |
|---|---|
| after | UHDRS TMS dropped to 36 points (14 points improvement), TFC increased to 8 points (2 points improvement), MoCA improved to 16 points, exercise and mood improved, weight gained |
| highlight | Tetrabenazine combined with nutritional support significantly improves exercise symptoms and nutritional status, and weight recovery improves overall prognosis. |