Huntington's Disease (HD)
Patient Condition
Advanced Huntington's disease, CAG repetition number 52, severe chore-like movements, severe cognitive decline, severe mental symptoms (delusions, hallucinations), complete dependence on nursing care. UHDRS TMS 58 points, TFC 4 points, MoCA 11 points.
Treatment Timeline
| Phase | Details | Date |
|---|---|---|
| integrated assessment | ||
| Drug symptomatic treatment + mental management | ||
| Comprehensive symptomatic treatment | ||
| Long-term maintenance management |
Treatment Outcome
| before | UHDRS TMS 58, TFC 4, MoCA 11, severe choreo-like movements, severe cognitive decline, delusion, complete dependence on nursing care |
|---|---|
| after | UHDRS TMS dropped to 42 points (16 points improvement), TFC increased to 6 points (2 points improvement), MoCA maintained at 11 points, motor and psychiatric symptoms were reduced, and nursing dependence was reduced |
| highlight | Tetrabenazine combined with antipsychotic drugs effectively controls late HD sports and psychiatric symptoms, and professional care improves quality of life |