Huntington's Disease (HD)
Patient Condition
Middle-advanced Huntington's disease, CAG repetition number 48, severe chorelike involuntary movements, moderate decline in cognition, obvious depressive and psychiatric symptoms, difficulty swallowing. UHDRS TMS 48, TFC 6, MoCA 15.
Treatment Timeline
| Phase | Details | Date |
|---|---|---|
| integrated assessment | ||
| Medication symptomatic treatment + rehabilitation | ||
| Optimization of comprehensive symptomatic treatment | ||
| Long-term maintenance management |
Treatment Outcome
| before | UHDRS TMS 48, TFC 6, MoCA 15, severe choreo-like exercise, moderate cognitive decline, depressive and psychiatric symptoms, dysphagia |
|---|---|
| after | UHDRS TMS dropped to 33 points (15 points improvement), TFC increased to 8 points (2 points improvement), MoCA improved to 17 points, choreo-like movements were reduced, and mental symptoms improved |
| highlight | Tetrabenazine combined with antipsychotic drugs effectively controls exercise and mental symptoms, and comprehensive symptomatic treatment improves quality of life. |