Huntington's Disease (HD)
Patient Condition
Middle-early Huntington's disease, CAG repetition number 45, moderate chore-like movement, moderate decline in cognitive function (memory and executive function), and mild manic symptoms. UHDRS TMS 35 points, TFC 9 points, MoCA 19 points.
Treatment Timeline
| Phase | Details | Date |
|---|---|---|
| multidisciplinary assessment | ||
| Drug initiation + comprehensive treatment | ||
| Optimization of comprehensive treatment | ||
| maintain management |
Treatment Outcome
| before | UHDRS TMS 35, TFC 9, MoCA 19, moderate choreo-like exercise, moderate cognitive decline, hypomania |
|---|---|
| after | UHDRS TMS dropped to 20 points (15 points improvement), TFC increased to 11 points (2 points improvement), MoCA improved to 22 points, motor and cognition improved, emotional stability |
| highlight | Deutrabenazine combined with mood stabilizers effectively controls motor and psychiatric symptoms, and cognitive rehabilitation simultaneously improves cognitive function |