CCA-018

Cholangiocarcinoma (CCA)

Houston 61 years old female United States Total Cost: 310

Patient Condition

Advanced intrahepatic cholangiocarcinoma recurred after surgery, positive for FGFR2 fusion gene (confirmed by FoundationOne CDx test), multiple liver metastases and retroperitoneal lymph node metastases, CA19 -9 680U/mL.

Treatment Timeline

PhaseDetailsDate
Diagnosis of postoperative recurrence
FGFR-targeted therapy
efficacy assessments
ongoing treatment for

Treatment Outcome

beforeAdvanced intrahepatic cholangiocarcinoma recurred after surgery, FGFR2 fusion positive, multiple liver metastases, CA19-9 680U/mL
afterAfter 14 cycles of Pemigatinib treatment, liver metastases shrank by 60%, CA19 -9 dropped to 120U/mL, reaching PR, and PFS exceeded 13 months
highlightTargeted treatment with Pemigatinib for FGFR2 fusion positive cholangiocarcinoma reduced liver metastases by 60%, and PFS exceeded 13 months