Patient Condition
The patient developed hands weakness and muscle atrophy at the age of 47, and was diagnosed with ALS (limb onset) at the age of 48. At the time of diagnosis, ALSFRS-R was 34, FVC was 76%, and the grip strength of both hands decreased. The progress rate is moderate (0.8 points per month). Enrolled mesenchymal stem cells combined with growth factor test.
Treatment Timeline
| Phase | Details | Date |
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| stem cell therapy | | |
| follow-up treatment | | |
| long-term follow-up | | |
Treatment Outcome
| before | ALSFRS-R 34 points, 0.8 points monthly drop, FVC 76%, weakness of both hands |
|---|
| after | ALSFRS-R 30 points, 2-year decrease of 4 points (83% delay), FVC 69% |
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| highlight | Intrathecal injection of UC-MSC combined with conventional treatment delayed progress by 83% |
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