Patient Condition
The patient developed left lower limb weakness at the age of 66, and was diagnosed with ALS (limb onset) at the age of 67. At the time of diagnosis, ALSFRS-R was 33, FVC was 70%, and left lower limb muscle strength was grade 3. Progress is rapid (monthly decrease of 1.1 points). Complicated with type 2 diabetes.
Treatment Timeline
| Phase | Details | Date |
|---|
| Combination therapy initiated | | |
| ongoing treatment for | | |
| maintenance treatment | | |
Treatment Outcome
| before | ALSFRS-R 33, monthly drop 1.1, FVC 70%, concurrent diabetes |
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| after | ALSFRS-R 26 points, 2-year decrease of 7 points (delay of 68%), FVC 58%(BiPAP support) |
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| highlight | Elderly ALS patients with diabetes have delayed progress by 68% through combination therapy, demonstrating the importance of comprehensive management |
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