Patient Condition
Mutazione del gene PRNP D178N (129M omozigoto), nonno con sospetta storia di FFI. Insomnia progressiva per 7 mesi, accompagnata da improvvisa perdita di peso di 15 kg, impotenza e anisocoria.
Treatment Timeline
| Phase | Details | Date |
|---|
| Symptom control and sleep induction | | |
| Immunomodulation and symptomatic treatment | | |
| Long-term maintenance and palliative care | | |
Treatment Outcome
| before | TST 42分钟/24h，体重骤降15kg，频繁攻击性发作，MMSE 20分 |
|---|
| after | TST改善至95分钟/24h，攻击性发作减少80%，体重稳定，营养状态改善 |
|---|
| highlight | 中国顶级神经内科中心的综合管理有效控制了行为和精神症状，姑息治疗显著改善了患者终末期生活质量 |
|---|