Rapamycin life extension plan
About
Rapamycin (sirolimus) is an immunosuppressant that mimics caloric restriction by inhibiting the mTOR signaling pathway. Caloric restriction is the most effective life-saving intervention known to date, extending the life of multiple model organisms. The core dilemma: ① The side effects of immunosuppression limit widespread application;② The optimal dose and dosing regimen are still controversial (5-10mg/week in the rich circle, which is much lower than the transplant dose);③ The side effects of long-term use of cardiac metabolism are not yet clear.
Features & Symptoms
- mTOR inhibitor
- Simulate caloric confinement effects
- Extend the life of model organisms
- Secret use by the rich circle
Treatment Options
| Treatment | Description | Stage | Price Range |
|---|---|---|---|
| Low-dose intermittent rapamycin | The popular life extension regimen in wealthy circles is 5-10mg per week, which is significantly lower than the transplant dose. The secret life-prolonging drug among Silicon Valley's wealthy circles is recommended by anti-aging experts such as Peter Attia. | 超适应症使用 | $3K - $8K/年 |
| Rapamycin + metformin combination | Combined mTOR inhibition and AMPK activation dual life-prolonging mechanism. The ATTACK study is evaluating the safety of the combination regimen in older adults. | 临床试验 | $5K - $12K/年 |
| Rapamycin Skin Test Kit | Personalized test to assess an individual's sensitivity to rapamycin and optimal dose. A must-have testing item before extending life in the rich circle. | 高端私人定制 | $2K - $5K/次 |
Prognosis
There is currently no cure, aiming to delay the aging process
Additional Notes
Notes: Applicable population: Healthy adults over 50 years old, without active infections or immune system diseases; dosage note: 5-10mg/week (intermittent dosing) is commonly used in the anti-aging field, which is much lower than the organ transplant dose (2-5mg/day); Side effect monitoring: Fasting blood glucose, lipid profile, immune cell count and renal function need to be monitored regularly; contraindicated population: immunocompromised patients, active infection patients, pregnant women; effect evaluation: The subjective energy improvement and metabolic improvement are clear, but there is a lack of hard endpoint data on life extension. Exclusive service commitment: The platform will allocate a dedicated health management team to each customer to assist in dismantling and properly deploying the following precautions throughout the process. When cross-state and cross-border diagnosis and treatment projects or drugs are involved, the platform will make overall arrangements for the entire docking; for disabled and semi-disabled customer groups, the platform will provide rush-free alternative solutions (including remote consultation, door-to-door sampling, direct drug delivery in the cold chain, etc.), to ensure that customers can receive the same high-quality health management services without having to travel in person.; Research phase: Off-label use/research. Prognosis: There is currently no cure and aims to delay the aging process.
Frequently Asked Questions
What is Rapamycin life extension plan?
Rapamycin (sirolimus) is an immunosuppressant that mimics caloric restriction by inhibiting the mTOR signaling pathway. Caloric restriction is the most effective life-saving intervention known to date, extending the life of multiple model organisms. The core dilemma: ① The side effects of immunosuppression limit widespread application;② The optimal dose and dosing regimen are still controversial (5-10mg/week in the rich circle, which is much lower than the transplant dose);③ The side effects of long-term use of cardiac metabolism are not yet clear.
What are the symptoms of Rapamycin life extension plan?
mTOR inhibitor,Simulate caloric confinement effects,Extend the life of model organisms,Secret use by the rich circle
How is Rapamycin life extension plan treated?
Low-dose intermittent rapamycin: The popular life extension regimen in wealthy circles is 5-10mg per week, which is significantly lower than the transplant dose. The secret life-prolonging drug among Silicon Valley's wealthy circles is recommended by anti-aging experts such as Peter Attia.; Rapamycin + metformin combination: Combined mTOR inhibition and AMPK activation dual life-prolonging mechanism. The ATTACK study is evaluating the safety of the combination regimen in older adults.; Rapamycin Skin Test Kit: Personalized test to assess an individual's sensitivity to rapamycin and optimal dose. A must-have testing item before extending life in the rich circle.
What is the prognosis for Rapamycin life extension plan?
There is currently no cure, aiming to delay the aging process