Metformin Life Extension Program
About
Metformin is a first-line medication for type 2 diabetes that improves insulin sensitivity and reduces liver glucose production and inflammatory response by activating AMPK. It has shown a life-saving effect in a variety of model organisms. The TARGET study is exploring the life-saving effects of metformin in healthy older adults. Core dilemmas: ① The evidence for life extension mainly comes from diabetic patients, and it is difficult to distinguish between hypoglycemic and life extension effects;② Gastrointestinal side effects affect long-term compliance.
Features & Symptoms
- AMPK activator
- improve insulin sensitivity
- reduce inflammatory response
- Extend the life span of nematodes and rodents
Treatment Options
| Treatment | Description | Stage | Price Range |
|---|---|---|---|
| Low-dose metformin sustained release tablets | A sustained release formulation of 500-1000mg per day was the dose used in the TARGET study. Improve metabolic parameters and insulin sensitivity. | 超适应症使用 | $500 - $2K/年 |
| Metformin + rapamycin combination | Combining the dual mechanisms of AMPK activation and mTOR inhibition is the core ingredient of the popular "longevity cocktail" in the rich circle. | 高端私人定制 | $3K - $8K/年 |
| Metformin Metabolism Test Package | A comprehensive test package to assess the effects of metformin on metabolic parameters, inflammatory markers and cognitive function. | 高端私人定制 | $3K - $8K/次 |
Prognosis
There is currently no cure, aiming to delay the aging process
Additional Notes
Notes: Applicable population: Healthy people over the age of 40 who have metabolic problems or are seeking to prolong life; Dose recommendations: TARGET study uses a sustained release formulation of 500-1500mg/day, which is recommended to be gradually tolerated from low doses; Side effects: Common gastrointestinal reactions (nausea, diarrhea), which can be alleviated with meals; Contraindicated population: severe liver and kidney dysfunction (eGFR<30), 48 hours before and after use of contrast media; Vitamin B12 monitoring: Long-term use can lead to vitamin B12 deficiency, and annual testing is recommended.; Exclusive service commitment: The platform will allocate a dedicated health management team to each customer to assist in dismantling and properly deploying the following precautions throughout the process. When cross-state and cross-border diagnosis and treatment projects or drugs are involved, the platform will make overall arrangements for the entire docking; for disabled and semi-disabled customer groups, the platform will provide rush-free alternative solutions (including remote consultation, door-to-door sampling, direct drug delivery in the cold chain, etc.), to ensure that customers can receive the same high-quality health management services without having to travel in person.; Study phase: Off label use/TARGET study. Prognosis: There is currently no cure and aims to delay the aging process.
Frequently Asked Questions
What is Metformin Life Extension Program?
Metformin is a first-line medication for type 2 diabetes that improves insulin sensitivity and reduces liver glucose production and inflammatory response by activating AMPK. It has shown a life-saving effect in a variety of model organisms. The TARGET study is exploring the life-saving effects of metformin in healthy older adults. Core dilemmas: ① The evidence for life extension mainly comes from diabetic patients, and it is difficult to distinguish between hypoglycemic and life extension effects;② Gastrointestinal side effects affect long-term compliance.
What are the symptoms of Metformin Life Extension Program?
AMPK activator,improve insulin sensitivity,reduce inflammatory response,Extend the life span of nematodes and rodents
How is Metformin Life Extension Program treated?
Low-dose metformin sustained release tablets: A sustained release formulation of 500-1000mg per day was the dose used in the TARGET study. Improve metabolic parameters and insulin sensitivity.; Metformin + rapamycin combination: Combining the dual mechanisms of AMPK activation and mTOR inhibition is the core ingredient of the popular "longevity cocktail" in the rich circle.; Metformin Metabolism Test Package: A comprehensive test package to assess the effects of metformin on metabolic parameters, inflammatory markers and cognitive function.
What is the prognosis for Metformin Life Extension Program?
There is currently no cure, aiming to delay the aging process