Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis
Summary
CONCLUSION Based on absolute risk reductions and thresholds considered clinically meaningful, this review found little to no benefits from use of calcium, vitamin D, or combined supplementation on the prevention of fractures and falls. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42023483915.
Content
# Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis
*Published: 2026 May 20*
## CONCLUSION
Based on absolute risk reductions and thresholds considered
clinically meaningful, this review found little to no benefits from use of
calcium, vitamin D, or combined supplementation on the prevention of fractures
and falls.
SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42023483915.
DOI: 10.1136/bmj-2025-088050